Biogen and Bio-Thera Reveal Tocilizumab Progress

Biosimilar Actemra Phase III Results Trigger $30m Payment Under April Deal

 
• By David Wallace
  
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Biogen and Bio-Thera Solutions have reported positive results from a Phase III trial for their BAT1806 proposed biosimilar tocilizumab rival to Actemra. The milestone has triggered a $30m payment from Biogen under the pair’s development deal.

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Biogen and Bio-Thera have announced Phase III results for their Actemra biosimilar • Source: Alamy

Biogen and China’s Bio-Thera Solutions have celebrated positive results from a Phase III trial for their proposed biosimilar to Actemra (tocilizumab), with the BAT1806 candidate meeting primary endpoints and showing “equivalent efficacy and comparable safety profile” in patients with moderate-to-severe rheumatoid arthritis inadequately controlled by methotrexate therapy.

The primary endpoint in the Phase III trial – a global, randomized, multi-center, double-blind, parallel-group study in 621 patients –...

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