Three BRICS Launch Generic Challenge For Vertex’s Landmark CF Therapy

Representatives Call Out Originator’s ‘Repeated Strategy Of Stubborn Negotiation’

With a suite of vastly expensive and advanced cystic fibrosis therapies entirely under its command, Vertex is facing more heat from patients and advocates in several major low- and middle-income countries.

Vertex
• Source: Shutterstock

Frustrated at ongoing lack of access in low- or middle-income countries to Vertex’s Trikafta/Kaftrio (elexacaftor/ivacaftor/tezacaftor) landmark treatment for cystic fibrosis, and with Vertex “making no effort to address this gross health inequality resulting from their business practice,” a coalition of activists and patients in four countries have commenced action to override the originator’s patents, including a bid for a compulsory license to the originator’s IP.

Three of the countries represented, Brazil, India and South Africa, form part of the five-strong BRICS, the leading emerging economic...

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