Five-Year LOE Impact Approaches $200bn

Stelara, Eylea, Vyvanse And Xarelto Among Key Targets For Biosimilars And Generics To 2028

As a number of major brands face generic and biosimilar competition, the loss-of-exclusivity impact across the leading 10 developed markets will approach $200bn over the next five years, according to a fresh medicines spending report running to 2028.

Purple icon reading $200bn
The impact of LOEs for the leading 10 developed markets from 2024 to 2028 is nearing $200bn • Source: Shutterstock

The total impact of brand losses of exclusivity in the next five years across the leading 10 worldwide markets has been valued at almost $200bn by the latest “Global Use of Medicines 2024” report from IQVIA.

“Across the leading 10 developed markets, the impact of brand LOEs in the next five years is expected to increase...

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