Could The Gut Cure Brain Disease?

Gut And Brain Heath Are Far More Intimately And Intricately Linked Than Previously Imagined

 
• By Melanie Senior
  
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Scientists now understand that there are multiple, bi-directional links between gut and brain. They are using this knowledge to develop new treatments for some of the most challenging chronic conditions, including Alzheimer’s disease, Parkinson’s disease and obesity. 

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The gut-mediated route to the brain offers several potential advantages for drug developers

Hippocrates (460-370BC) believed that all diseases begin in the gut. He was closer to the truth than he has been given credit for. It is reasonable to assume that gastro-intestinal disorders or metabolic diseases may start in the gut. But research over the last 15 years into the nature and role of the gut microbiome – the trillions of microorganisms that reside in our intestine – has uncovered its far wider influence, including across many auto-immune conditions, cardiovascular disease and even cancer.

Even then, few would have linked gut health to Parkinson’s, autism or Alzheimer’s. Yet gut and brain health are far...

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