Vertex still aims to convince NHS England and NICE, the health technology appraisal institute for England and Wales, that its proposed portfolio approach is the best way to get its cystic fibrosis drug, Orkambi (lumacaftor/ivacaftor) to patients and “get ahead” of certain problems in the reimbursement process. Despite the NHS England turning down the proposal last week, Vertex believes that it could repeat the success of this approach in the UK that it has seen in Ireland.
The deal that the company put forward to NHS England in February this year is similar to the approach used...








