Brachial Plexus Clinical Trial Efficacy Results:

"In this study, there was a statistically significant treatment effect for EXPAREL compared to placebo in cumulative pain scores through 48 hours as measured by the AUC of the visual analog scale (VAS) pain intensity scores. There were statistically significant, but small differences in the amount of opioid consumption through 48 hours, the clinical benefit of which has not been demonstrated. For those patients who required rescue medication, the mean amount of morphine-equivalent opioid rescue used over 48 hours was 12 mg for patients treated with EXPAREL and 54 mg for patients treated with placebo and 23 mg with EXPAREL vs. 70 mg for placebo over 72 hours."
"Although at 48 hours, 9 subjects (13%) in the EXPAREL group remained opioid-free compared to 1 subject (1%) in the placebo group, a difference which was statistically significant, at 72 hours, there were 4 (6%) subjects in the EXPAREL group who remained opioid-free compared to 1 (1%) subject in the placebo group, a difference that is not statistically significant."

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