What Will Trigger Modification Of COVID-19 Vaccines?

 
• By Brenda Sandburg
  
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US FDA’s advisory committee members question when it will be clear current vaccines are not providing sufficient protection and express concern about the time it will take to change their composition given the need for clinical data to gain authorization.

Rabbit hole
US FDA advised not to go down a rabbit hole in deciding when to modify COVID-19 vaccines • Source: Alamy

The US Food and Drug Administration is coming up with a process to change the composition of COVID-19 vaccines as their effectiveness declines over time. But many questions remain unresolved, such as when it is clear current vaccines are providing insufficient protection and if manufacturers will be able to alter the strains fast enough to have an impact.

The agency’s Vaccines and Related Biological Products Advisory Committee considered these issues at its 6 April meeting. Members agreed that...

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