‘Eye-Popping Cost Of Redundancy:’ Will US Market Find Place For RSV Prevention Meds And Vaccines?

A CDC work group seems to be leaning towards recommending choosing either Pfizer’s maternal vaccination for infant RSV or AstraZeneca/Sanofi’s preventative antibody treatment in babies but not both, in part due to the high costs. What happens to the already available Synagis antibody is another wildcard. 

Child on respirator
RSV prevention medications and vaccines may fill specific niches when on the market together. • Source: Shutterstock

The high ratio of cost-to-effectiveness in preventing RSV in infants by both vaccinating the expectant mother and giving the infant a preventative monoclonal antibody likely means that a dual approach is out of the question in most cases, but figuring out which maternal-child pairs should get which product could also be quite burdensome on the US health care system.

Key Takeaways

  • CDC working group suggests there are few cases where both maternal RSV vaccination and infant monoclonal antibody protection are needed, though neither product seems to be clearly preferential.

If both RSVpreF, Pfizer Inc.’s maternal respiratory syncytial virus vaccine, and AstraZeneca PLC/Sanofi’s nirsevimab gain US Food...

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