Spark Therapeutics priced its initial public offering at $23 per share and the company's stock closed its first day of trading up 117.4% at $50, showing that investors are willing to place big bets on gene therapy that could cure or substantially reduce treatment burdens for severe diseases and conditions.
Philadelphia, Pennsylvania-based Spark, which could have the first US FDA-approved gene therapy, will gross at least $161m from the sale...


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