Vical plummets on placebo promise in herpes study

 
• By Mandy Jackson
  
Generate a summary of this article
Listen to this article
Beta

San Diego-based Vical's stock was cut almost in half on 23 June after the company reported that the placebo in a Phase I/II clinical trial outperformed both the monovalent and bivalent forms of its therapeutic genital herpes vaccine by a wide margin. In terms of the trial's primary endpoint, viral shedding decreased 12% for patients treated with the monovalent vaccine, 19% in the study's bivalent arm and 45% in the placebo group.

San Diego-based Vical's stock was cut almost in half on 23 June after the company reported that the placebo in a Phase I/II clinical trial outperformed both the monovalent and bivalent forms of its therapeutic genital herpes vaccine by a wide margin. In terms of the trial's primary endpoint, viral shedding decreased 12% for patients treated with the monovalent vaccine, 19% in the study's bivalent arm and 45% in the placebo group.

Changes in lesion rate and viral load – secondary endpoints in the study – were statistically significant, so longer-term safety...

Scrip Podcast

Keep up with the top pharma business news of the week. On the go.

Scrip brings you a weekly bulletin of top picks.

SpotifyApple PodcastsWebsite

More from Anti-infective

More from Therapeutic Category