Does CheckMate 026 Take Bristol Out Of The End Game?

Failure of Bristol's Opdivo in patients with lower expression of PD-L-1 biomarker gives Merck's Keytruda a huge advantage in first-line lung cancer, and leaves market-leading Bristol to wait for combination data.

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Bristol-Myers Squibb Co. has enjoyed a long run as the golden child of immuno-oncology, but its attempt to corner an even larger section of the market appears to have lost it a shot at the biggest segment of all.

The firm's Aug. 5 announcement that its PD-1 inhibitor Opdivo missed the primary progression-free-survival endpoint in the much-anticipated CheckMate 026...

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