A completely new form of therapy, the use of viruses to kill cancer cells, is now recommended by NICE for use in melanoma patients in England in final draft guidance, although its future therapeutic and commercial success may depend on positive findings from ongoing combination studies with checkpoint inhibitors and other immunotherapies.
Amgen Inc.’s oncolytic virus-based immunotherapy Imlygic (talimogene laherparepvec) has been cleared for use in melanoma patients by the UK’s National Institute for health and Care Excellence (NICE), at the second time of asking.
The recommendation in NICE’s final draft guidance came after Amgen put in place a patient access scheme (PAC) in which...
The Swiss pharma company is rebalancing the portfolio, emphasizing best-in-class drugs and moving into new areas like cardiovascular and metabolic disease.
In this week's episode: Trump’s UK drug pricing win; Novo explains semaglutide Alzheimer's rationale; J&J and Novartis on this year’s biggest M&A deals; a look at the mixed performance of CAR-Ts; and Akeso’s goals beyond ivonescimab.
Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Lilly's first Phase III triplet win opens the door to a label expansion in BTK-pretreated CLL, with analysts suggesting Jaypica could attain blockbuster status. However, the window to capitalize may be brief as next-generation BTK degraders close in with head-to-head trials.
Mounjaro, Eliquis, and Darzalex buck the Q1 trend to make gains
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