UK HTA gives provisional backing to Merck’s once-daily fixed-dose hepatitis C combo Zepatier after the US drug maker offers an undisclosed price cut.
The National Institute for Health and Care Excellence (NICE) has provisionally okayed use of Merck & Co. Inc.’s Zepatier (elbasvir and grazoprevir) as a treatment for adults with chronic hepatitis C virus genotypes 1 or 4 infection, with or without ribavirin, on Britain’s publicly funded National Health Service (NHS).
The once-daily fixed-dose combination tablet containing 50 mg of elbasvir, an NS5A inhibitor, and 100 mg of grazoprevir, a NS3/4A...
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PolyPid's D-PLEX100 meets Phase III endpoints this time around, significantly reducing surgical point infections in abdominal colorectal surgery, and is set for a US approval submission early next year.
The company will ramp up manufacturing of its Jynneos vaccine to meet demand in worst-affected African countries and stockpiling richer nations.
2030 sales forecasts for Novo’s obesity hope are an order of magnitude larger than its closest rival among 2025’s expected debutantes.
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Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
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