Takeda's Ninlaro Back In European Myeloma Race After CHMP Turnaround

 
• By Francesca Bruce
  
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A CHMP about turn on Takeda's Ninlaro (ixazomib) for multiple myeloma means the Japanese firm is back on track to compensate for lost revenues from the impending patent expiry of key product Velcade. However, the Japanese firm will have a tough time ensuring Ninlaro is not overshadowed by rivals.

Europe

The European Medicines Agency's CHMP has reversed its initial negative opinion on Takeda Pharmaceutical Co. Ltd.'s Ninlaro (ixazomib) and has now green-lighted a conditional approval. The news will come as a relief for Takeda, which will now be better poised to offset a decline in sales from Velcade (bortezomib) following impending patent expiry. However, Takeda cannot afford to relax: it will have to work hard to establish Ninlaro in an increasingly crowded market while approval of a promising rival from Janssen looms.

On Sept. 15 the CHMP recommended conditional approval of Ninlaro in combination with lenalidomide (Celgene Corp.'s Revlimid) and dexamethasone...

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