ASH Ends With Consistent Kite CAR-T Data, Some Hope For Juno

Kite reported interim results for KTE-C19 from the ZUMA-1 study that showed efficacy consistent with earlier results without the deaths from neurotoxicity that have plagued Juno, but Juno’s latest CAR-T offering may carry fewer safety concerns.

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The American Society of Hematology annual meeting helped set the stage for what could be the first chimeric antigen receptor T-cell (CAR-T) therapies approved in the US with Kite Pharma Inc. maintaining its spot as a leader in the field, while Juno Therapeutics Inc. continues to face questions about safety.

Kite’s latest data from the ZUMA-1 clinical trial, which is expected to support US FDA approval of the CAR-T therapy...

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Fosun ALK/ROS1 Inhibitor Shows 1L Promise In Advanced NSCLC

 
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Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.

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Fosun ALK/ROS1 Inhibitor Shows 1L Promise In Advanced NSCLC

Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.

Allarity Hopes To Breathe New Life Into Ixempra In Breast Cancer

The US precision medicine company hopes its drug response predictor technology will enhance responses to the chemotherapy Ixempra on the basis of promising data from a handful of breast cancer patients in a Phase II trial, marking a positive turn in its journey to date.  

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Spotlight On RDCs, AOCs As Leading Novel Bioconjugates[Updated]

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Fosun ALK/ROS1 Inhibitor Shows 1L Promise In Advanced NSCLC

Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.