Pain Licensing: Upfront Gains Fall As Deals Get More Experimental

229 alliance deals were signed in the pain management sector between 2012 and November 2016, worth more than $1bn in upfront payments and around $11bn in total potential value. But an increase in deals for riskier, earlier stage assets has pushed down upfront payment values for the sector, knocking it out of sync with other therapy areas.

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Pain management deals were worth more than $11bn between 2012 and 2016 • Source: Shutterstock

Surprisingly, companies developing pain therapeutics – a well-served market – are also some of the most prolific researchers, with more than 341 Phase I to Phase III/IV active clinical trials as of November 2016. The sector has also signed 229 pain management-focused deals over the last five years, worth a combined $11bn in total potential value.

This value ranks pain partnerships as some of the most lucrative within the CNS field, according to data from Informa...

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