Pfizer has turned again to external expertise among US biotechs to find a potential gene therapy for hemophilia A, to add to its two-year collaboration with Spark Therapeutics on a gene therapy for hemophilia B, and beating off strong competition from other suitors in the process.
Pfizer Inc. has strengthened its gene therapy research pipeline and its interests in next-generation hemophilia therapies by exclusively licensing worldwide Sangamo BioSciences Inc.’s hemophilia A gene therapy program. The lead project, SB-525, is expected to enter initial clinical studies this quarter, having already been cleared to do so by the US FDA.
The deal is estimated to be worth around $545m for Sangamo, the companies announced on May 10, and will see...
The Swiss pharma company is rebalancing the portfolio, emphasizing best-in-class drugs and moving into new areas like cardiovascular and metabolic disease.
Merck’s immuno-oncology blockbuster was the world’s best-selling drugs by revenues for the second year in a row, with an almost $12bn lead over its closest rival, Novo Nordisk’s GLP-1 drug Ozempic.
Francesco Hofmann, head of R&D at the mid-sized French group, tells Scrip that its strategy of not playing in the spaces that are dominated by big pharma is paying off.
Companies stand a better chance of securing public reimbursement in Mexico for innovative medicines if they understand changing approaches to healthcare. The shift means the emergence of managed entry agreements and a focus on economic impact, explains AMIIF, Mexico's research-based pharmaceutical industry association.
Novartis’s APMA chief outlines the company’s tailored approach to deliver long-term outcomes, novel access solutions via innovative financing options and shape the CVD disease ecosystem in the extraordinarily diverse region. Partnering to build AI infrastructure is another key prong.
A court order encompassing funding, drug pricing, clinical trials and overall policy implementation aspects is expected to bring about a paradigm shift in the treatment of rare diseases in India. Sarepta, Roche and Sanofi are among the key players that have been part of pricing discussions.
