J.P. Morgan Notebook Day 4: CRISPR's Not Worried; Theratechnologies' HIV Niche; And Is Moderna's IPO Coming Soon?

 
• By Jessica Merrill, Mandy Jackson, and Emily Hayes
  
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Daily round-up of news and notes from the 2018 J.P. Morgan Healthcare Conference: Alder's Options for CGRP drug; CRISPR's not worried about Cas9 controversy; Theratechnologies seeks more HIV niche products; Moderna is shaping up to have a big 2018; TG Therapeutics and Immunomedics milestones ahead.

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Alder BioPharmaceuticals Inc. was talking to potential partners at J.P. Morgan for its calcitonin gene-related peptide (CGRP) drug eptinezumab, which has shown promising efficacy in Phase III clinical trials. The company released positive Phase III data on the migraine treatment during the conference, which ran Jan. 8-11 in San Francisco, showing 15% of patients treated with the drug experienced a 100% response for three months following a single intravenous infusion; 61% achieved a 50% reduction in migraine days or greater from baseline.

The company is still awaiting some additional data readouts from the four studies that make up the clinical program for...

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