CDK4/6 Inhibitor Market Snapshot: New Drugs Jockey For A Piece Of The Multi-Billion Dollar Pie

Pfizer's Ibrance has a strong lead in the CDK4/6 space, but Novartis' Kisqali and Lilly's Verzenio are looking to carve out their own niches, expand the category and move into earlier treatment settings. Another scramble is on as well, to answer the question: what comes next?

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Three cyclin-dependent kinase (CDK) 4 and 6 inhibitors are now on US market for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer in various combinations with hormonal therapy, setting the category up for a competitive show down.

Novartis AG's Kisqali (ribociclib) and Eli Lilly & Co.'s Verzenio (abemaciclib) are the drugs that are coming from...

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