Five years after the Swiss major presented positive Phase II data on inclacumab as a treatment for patients with acute coronary syndromes, the drug has been snapped up by Global Blood Therapeutics for a tiny upfront fee to be developed for sickle cell disease.
Roche has become the latest pharmaceutical major this week, after Gilead Sciences Inc., to unload what was once seen as a promising asset, handing inclacumab over to Global Blood Therapeutics Inc. for just $2m upfront.
The Swiss major has licensed inclacumab, a monoclonal antibody against P-selectin, to GBT, which plans to develop it for vaso-occlusive...
A disastrous Phase II miss for the pulmonary arterial hypertension candidate AV-101 leaves Aerovate drifting. Could Gossamer stand to benefit?
2030 sales forecasts for Novo’s obesity hope are an order of magnitude larger than its closest rival among 2025’s expected debutantes.
GLP-1 receptor agonists could play a big role in tackling neurodegeneration and a new academic study has raised expectations of Novo Nordisk’s latest semaglutide Phase III results
CEO Bill Anderson would not be drawn on whether the drug, currently approved for chronic kidney disease associated with type 2 diabetes, will hit a previous forecast of €3bn peak sales, but expansion into heart failure may make that figure look conservative.
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Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
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