Farxiga Data Change Heart Failure Treatment Outlook

Sep 02 2019

• By Eleanor Malone

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DAPA-HF data on AstraZeneca’s SGLT-2 inhibitor dapagliflozin as a treatment for heart failure in both diabetics and non-diabetics won spontaneous applause at ESC.

Heart

Diabetes drug Farxiga/Forxiga (dapagliflozin) looks set to become a new standard of care in the treatment of heart failure based on the results of the DAPA-HF Phase III trial presented at the European Society of Cardiology Congress in Paris, France on 1 September 2019. The product reduced the composite endpoint of cardiovascular death or worsening heart failure by 26% when given on top of standard of care and the benefits were seen in both diabetic and non-diabetic patients.

The sodium glucose cotransporter-2 (SGLT-2) inhibitor has stolen a march on rivals in its class with regulatory filings slated by...

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