Sarepta Secures $1.15bn From Roche In Ex-US DMD Gene Therapy Deal

Including upfront payments, half of development costs for SRP-9001, $1.7bn in milestone fees and royalties on sales outside the US, Sarepta pegs deal’s value at $10bn-plus.

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Roche will lead SRP-9001 commercialization in all countries outside the US.

Sarepta Therapeutics Inc. CEO Doug Ingraham said that out-licensing ex-US rights to its Duchenne muscular dystrophy (DMD) gene therapy SRP-9001 to Roche eventually will bring the company more than $10bn in benefit. Initially, Sarepta gets $1.15bn under the deal announced on 23 December that, when combined with cash on hand, will give the company $2.5bn to advance its plans for being a global gene therapy leader.

The agreement comes barely a week after Roche closed its acquisition of gene therapy specialist Spark Therapeutics Inc. following...

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