Roche's Tecentriq Notches Approval For First-Line NSCLC Monotherapy

The company is getting more attention these days for its TIGIT inhibitor tiragolumab in combination with Tecentriq for 1L NSCLC, but a new 1L monotherapy indication for Tecentriq helps it compete against Keytruda. 

Digital illustration of lung cancer cells in color background

The next big thing lined up for Roche in lung cancer is its dual checkpoint approach of its novel TIGIT inhibitor tiragolumab plus its stalwart PD-L1 inhibitor Tecentriq. But the 18 May approval of Tecentriq monotherapy for first-line non-small cell lung cancer is an important step in the company’s strategy of building its way into immuno-oncology dominance by thorough execution.

Roche ceded the early lead in immuno-oncology to Bristol-Myers Squibb Co. and Merck & Co. Inc., but the...

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