Regeneron's Evkeeza Approved For Ultra-Rare Genetic High Cholesterol – And Priced To Match

Evkeeza is the first ANGPTL3 approved by the FDA; Regeneron scientists discovered the angiopoetin gene family.

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Regeneron's Evkeeza is approved for an ultra-rare disease • Source: Shutterstock

Regeneron Pharmaceuticals, Inc. will target Evkeeza (evinacumab-dgnb) to an ultra-rare patient population with homozygous familial hypercholesterolemia (HoFH) and price it in the range that has become commonplace for drugs for ultra-rare conditions. The wholesale acquisition cost (WAC) in the US is based on weight but is expected to be approximately $450,000 per year on average, the firm said.

The US Food and Drug Administration approved Evkeeza for patients 12 and older with HoFH as an adjunct to other...

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