Aptose Biosciences Inc. has reached an exclusive global license agreement worth up to $420m with Hanmi Pharmaceutical Co., Ltd. to develop and commercialize in all indications HM43239, the major South Korean firm's oral myeloid kinome inhibitor that targets multiple kinases in myeloid malignancies, including SYK and FLT3.
Hanmi will receive $12.5m upfront, comprising $5m in cash and $7.5m in Aptose shares, plus up to $407.5m contingent on...








