Merck has already paused other studies testing the potential first-in-class NRTTI and is adding additional monitoring of lymphocyte and CD4+ T-cell assessments.
Merck & Co., Inc. has been hoping to break into the pre-exposure prophylaxis (PrEP) market for people at high risk of HIV-1 infection with its first-in-class nucleoside reverse transcriptase translocation inhibitor (NRTTI) islatravir, but the company announced it is pausing enrollment in more studies testing the drug, broadening the setback for the program.
The company said on 6 December that it is pausing enrollment in two Phase III clinical trials, IMPOWER 22 and...
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PolyPid's D-PLEX100 meets Phase III endpoints this time around, significantly reducing surgical point infections in abdominal colorectal surgery, and is set for a US approval submission early next year.
The company will ramp up manufacturing of its Jynneos vaccine to meet demand in worst-affected African countries and stockpiling richer nations.
2030 sales forecasts for Novo’s obesity hope are an order of magnitude larger than its closest rival among 2025’s expected debutantes.
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Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
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