Janssen/Legend Plan Phased US Launch For BCMA-Targeting CAR-T Carvykti

First Multiple Myeloma Patient Could Be Infused In Six Weeks

Janssen priced the one-time autologous treatment at $465,000, well above the $419,500 list price for Bristol’s first-to-market CAR-T, but expects broad commercial and Medicare coverage. 

Red balloon mid air amongst wooden square cubes
A phased launch will allow for careful certification of treatment centers • Source: Alamy

Janssen Pharmaceutical Cos. and Legend Biotech Corp. plan a phased launch of their newly approved autologous chimeric antigen receptor T-cell (CAR-T) multiple myeloma therapy Carvykti (ciltacabtagene autoleucel), which targets B-cell maturation antigen (BCMA) on myeloma cells, to make sure treatments centers are ready to properly administer the complex product.

Johnson & Johnson’s Janssen subsidiary and Legend will launch Carvykti at a list price of $465,000 for the one-time...

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