Gut-Brain Connect: How metaMe’s Digital Therapeutic Hopes To Rewire IBS Treatment

metaMe Health CEO and ex-Takeda executive Tim Rudolphi and partner firm Indegene’s senior vice president Marut Setia discuss with Scrip plans for the FDA-authorized, gut-directed hypnotherapy Regulora, including an openness to outcomes-based pricing and the wider go-to-market strategy.

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Digital Therapeutics Set To Redefine IBS Therapy? • Source: Alamy

There’s a growing body of science on the gut-brain connection and that gut-feeling or gut-wrenching pain may well be a type of message from your enteric nervous system or “second brain”, as medical experts refer to it. Importantly, that “brain in your gut” communicates effectively with the big brain in the head.

“Our two brains ‘talk’ to each other, so therapies that help one may help the other,” notes Dr Jay Pasricha,...

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Spotlight On RDCs, AOCs As Leading Novel Bioconjugates[Updated]

Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.

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EHA: Lilly’s Jaypirca Posts First Phase III Triplet Win In CLL While BTK Degraders Advance

Lilly's first Phase III triplet win opens the door to a label expansion in BTK-pretreated CLL, with analysts suggesting Jaypica could attain blockbuster status. However, the window to capitalize may be brief as next-generation BTK degraders close in with head-to-head trials.

EHA: Lilly’s Jaypirca Posts First Phase III Triplet Win In CLL While BTK Degraders Advance - Clone

Lilly's first Phase III triplet win opens the door to a label expansion in BTK-pretreated CLL, with analysts suggesting Jaypica could attain blockbuster status. However, the window to capitalize may be brief as next-generation BTK degraders close in with head-to-head trials.