ASCO: AstraZeneca's Enhertu Is Poised To Change The Breast Cancer Paradigm

 
• By Jessica Merrill
  
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The results of DESTINY-Breast04 could impact survival for approximately 50% of patients diagnosed with metastatic breast cancer today, principal investigator Modi said at the American Society of Clinical Oncology annual meeting.

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AstraZeneca PLC and Daiichi Sankyo Co., Ltd. teased the possibility that the Phase III DESTINY-Breast04 study testing Enhertu (trastuzumab deruxtecan) in individuals with breast cancer categorized as HER-2 low was potentially paradigm-changing months ago with the release of top-line data, and the level of benefit seen in the full data presented at the American Society of Clinical Oncology (ASCO) meeting on 5 June clinched it.

The data are poised to change the way doctors think about categorizing breast cancer nearly 25 years after Genentech,...

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