Top 5 Deals Of 2022: The Economic Drag On M&A Continues

Many of the same factors that held down large M&A transactions in 2021 carried over to 2022, which saw eight buyouts valued at $2bn+, headlined by Amgen’s $27.8bn purchase of Horizon.

Top 5 Deals
Amgen's 12 December buyout of Horizon topped the list of 2022's five biggest deals • Source: Shutterstock

The economic factors that created a drag on major deal-making in the biopharmaceutical sector in 2021 continued into 2022. Up until December, it seemed like a second year in a row with a top deal of about $11.6bn – but Amgen, Inc.’s $27.8bn acquisition of Horizon Therapeutics plc closed out the year with a bang, and a new top deal.

Both 2022 and 2021 significantly trail the top deal values seen in 2020, and the averages seen pre-pandemic. However, with...

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