Lilly Wants To Gamble On Dice’s Oral IL-17 Drugs For Psoriasis

Lilly agrees to pay about $2.4bn to acquire Dice and its Phase IIb oral IL-17 inhibitor, as well as a discovery platform that has yielded a preclinical oral PD-L1 inhibitor.

Tumbling dice
Lilly is rolling the dice on oral IL-17 inhibitors in psoriasis • Source: Shutterstock

In a deal that may bring Eli Lilly and Company an oral alternative to blockbuster Taltz (ixekizumab) for psoriasis, the Indianapolis pharma unveiled an agreement on 20 June to acquire DICE Therapeutics, Inc. for approximately $2.4bn, the sixth-largest biopharmaceutical M&A deal of 2023.

Under the deal, expected to close in Q3, Lilly would acquire Dice’s pipeline of oral interleukin-17 inhibitors as well as...

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