Blueprint RETreats As It Sells US Gavreto Rights To Rigel

Drug Will Be Pulled In Most Markets

 
• By Alaric DeArment
  
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After sales of the RET inhibitor have been commercially disappointing, Blueprint said it is selling US rights to the drug to Rigel for $15m up front and potentially more than $100m in milestones.

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Rigel Pharmaceuticals, Inc. is beefing up its product portfolio with one of the only two RET inhibitors on the market, Blueprint Medicines Corporation’s Gavreto (pralsetinib), with its purchase of US rights from Blueprint for potentially more than $100m. Blueprint, meanwhile, is offloading a drug that had proven commercially disappointing, and in addition to selling US rights it plans to cease marketing of Gavreto outside the US and Greater China.

The deal, announced 22 February, is meant to coincide with the termination of Blueprint’s partnership with Roche Holding AG....

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