The market for biopharmaceutical company initial public offerings and follow-on public offerings has become more friendly this year, but some firms still are circumventing the public offering route and pursuing private investment in public equity (PIPE) financings to extend their cash runways. Denali Therapeutics Inc., Avidity Biosciences, Inc., Crinetics Pharmaceuticals, Inc. and Ocular Therapeutix, Inc. recently cashed in, grossing nearly $1.6bn between them from PIPE investors.
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