Physician Familiarity May Determine Epkinly Uptake In Follicular Lymphoma

Newly Approved Drug Going Up Against Roche’s Lunsumio

 
• By Alaric DeArment
  
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AbbVie/Genmab’s anti-CD20 bispecific is the first subcutaneous drug in the class to win approval for FL, but despite that advantage, doctors may pick the drug they know best.

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AbbVie Inc. and Genmab A/S scored a significant competitive advantage for their partnered Epkinly (epcoritamab-bysp) as the CD20xCD3-directed bispecific antibody won accelerated approval from the US Food and Drug Administration for third-line and later follicular lymphoma (FL), on top of its existing approval for third-line and later diffuse large B-cell lymphoma (DLBCL). However, despite having the advantage of easier administration, how it fits in the market with competitors may end up boiling down to physicians’ experience and preference.

The 26 June approval places Epkinly in direct competition with Roche Holding AG’s Lunsumio (mosunetuzumab-axgb). Lunsumio also has accelerated...

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