Analysts are split on the future for acasunlimab after the German biotech pulled out of co-development but Genmab is all set to kick off a Phase III trial in metastatic non-small-cell lung cancer for the bispecific antibody which acts on 4-1BB, a receptor expressed on activated T cells and natural killer cells.
Genmab A/S's ability to drive compounds through late-stage trials on its own will be put to the test following the news that BioNTech SE has pulled out of a pact to further co-develop acasunlimab for lung cancer.
The Danish biotech is assuming sole responsibility to advance acasunlimab, a PD-L1 x 4-1BB bispecific antibody, after its Germany-headquartered partner...
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
The US precision medicine company hopes its drug response predictor technology will enhance responses to the chemotherapy Ixempra on the basis of promising data from a handful of breast cancer patients in a Phase II trial, marking a positive turn in its journey to date.
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Pipelines in bioconjugates continue to develop, from ADCs to XDCs, with radionuclide drug conjugates (RDCs) and antibody-oligonucleotide conjugates (AOCs) leading the expansion.
Interim results from the Phase III REMARK study presented at WCLC showed the Chinese company’s second-generation ALK/ROS1 inhibitor met its primary endpoint as a first-line therapy in ALK-positive advanced NSCLC.
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