Cigna’s Bradbury Talks PCSK9 Contracts And Value Versus Volume

Amgen and Sanofi/Regeneron will pay deeper discounts if patients taking Repatha and Praluent don’t experience similar levels of LDL-cholesterol lowering as was seen in clinical trials.

Cigna Corp. has signed value-based contracts for the two PCSK9 inhibitors on the market for high cholesterol, linking reimbursement to LDL-C reduction, but the insurer also hopes to analyze data for cardiovascular outcomes. Cigna announced the new contracts for Amgen Inc.’s Repatha (evolocumab) and Sanofi/Regeneron Pharmaceuticals Inc.’s Praluent (alirocumab) May 11.

The contracts represent the first time an insurer has unveiled a value-based agreement for its commercial business with both PCSK9...

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