CicloMulsion Trial Failure Leaves NeuroVive Dependent On NeuroSTAT

 
• By Sten Stovall
  
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NeuroVive of Sweden pulled the plug on its lead cyclophilin inhibitor after it showed no benefit in preventing acute kidney injury in patients treated with the therapy prior to open heart surgery – but the specialty pharma says it has other early assets to concentrate on now.

The failure of NeuroVive Pharmaceutical AB's investigational medicine CicloMulsion in the mid-stage CiPRICS study has prompted the Swedish specialist pharma to end the therapy's development and focus instead on another formulation of essentially the same drug, NeuroSTAT, currently being tested in treatment of moderate to severe traumatic brain injury.

The unsuccessful CiPRICS, or Cyclosporine to Protect Renal Function In Cardiac Surgery, study was a double-blind, placebo-controlled, exploratory Phase II...

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