AbbVie Validates Voyager’s One-Shot Approach With Parkinson’s Collaboration

 
• By Jo Shorthouse
  
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AbbVie and existing partner Voyager Therapeutics are attempting to cross the blood-brain barrier with a new collaboration on vectorized antibodies to treat Parkinson’s disease and other synucleinopathies such as Lewy body dementia and multiple system atrophy.  

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Voyager Therapeutics Inc. has received another important validation for its CNS gene therapy approach by signing a collaboration with existing partner AbbVie Inc. on Feb. 22 that will see the pair develop and commercialize "vectorized antibodies" for Parkinson's disease and other diseases characterized by the abnormal accumulation of misfolded alpha-synuclein protein.

Several analysts are encouraged by this deal, with BTIG stating that it could lead to the “first true disease-modifying therapy...

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