Deciphera's Ripretinib Cuts GIST Death Risk By 64%; US Filing On Track For Early 2020

 
• By Leah Samuel
  
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Overall survival for patients with gastrointestinal stromal tumors (GIST) in the fourth-line setting was 15.1 months versus 6.6 months for placebo, building on impressive progression-free survival results.

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Deciphera encouraged by overall survival data

An encouraging improvement in overall survival in the Phase III INVICTUS clinical trial for Deciphera Pharmaceuticals Inc.'s ripretinib build on previously reported progression-free survival data and keep the company on track to seek US Food and Drug Administration approval in early 2020 for its kinase inhibitor in the fourth-line treatment of gastrointestinal stromal tumors (GIST).

Data presented at the European Society for Medical Oncology (ESMO) Congress on 30 September in Barcelona showed median overall survival...

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