Alnylam’s Full Lumasiran Dataset Seen As Confirming Approvability

 
• By Joseph Haas
  
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Building on data first reported last December, lumasiran appears on pace for approval by the December 2020 action date, but Dicerna still may show its drug is best-in-class.

Alnylam appears on track for its third RNAi therapeutic approval

Alnylam Pharmaceuticals Inc. reported detailed results from the Phase III ILLUMINATE-A study of lumasiran in primary hyperoxaluria type 1 (PH1) on 7 June, and while analysts are saying the RNA interference (RNAi) candidate is clearly approvable in the ultra-orphan indication, they also think the data leave room for competing drugs being developed for the disease.

As Alnylam presented the full ILLUMINATE-A dataset at the European Renal Association-European Dialysis and Transplant Association virtual conference, the biotech...

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