RNAi Partners Vie To Lead Race To Cure Hepatitis B

 
• By Joseph Haas
  
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At EASL 2020, four partnerships updated RNA-interference or antisense efforts to reduce hep B surface antigen, believed to lead to functional cure of the virus. One analyst sees J&J/Arrowhead as the early leader.

Hepatitis B
Four partnerships are working toward HBV functional cure with RNAi/antisense technology

Four partnerships employing RNA-interference or antisense therapeutic approaches to treating hepatitis B reported data from mid-stage programs during the European Association for the Study of the Liver’s virtual conference held 27-29 August. It’s early in the race but Datamonitor Healthcare analyst Michael Haydock sees the Johnson & Johnson/Arrowhead Pharmaceuticals, Inc. partnership holding an early lead in potentially achieving a functional cure for the virus, pursued most closely by GlaxoSmithKline plc and Ionis Pharmaceuticals, Inc.

Also in the race and worth watching, but behind the pace for now, according to Haydock, are Roche Holding...

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