Iovance Sparks More Optimism About Lifileucel’s Commercial Potential With New Analysis

 
• By Alaric DeArment
  
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The company is presenting an updated Phase II analysis at SITC as it prepares to complete its rolling BLA submission and readies its commercial launch.

Iovance presented updated data from its Phase II study of lifileucel at SITC • Source: Shutterstock

An updated Phase II analysis for Iovance Biotherapeutics, Inc.’s tumor-infiltrating lymphocyte (TIL) cell therapy lifileucel in melanoma gives a better idea of its efficacy potential and also might improve its chances for commercial success. The new look comes as the company works to complete a rolling biologics license application submission to the US Food and Drug Administration and prepares for the TIL product’s launch as one of the first approved cell therapies for a solid tumor indication.

Iovance presented pooled data from cohorts 2 and 4 in the pivotal Phase II C-144-01 trial of lifileucel in heavily...

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