Astellas Reports Second Phase III Win With Zolbetuximab In Stomach Cancer

 
• By Joseph Haas
  
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The anti-Claudin-18.2 agent plus chemotherapy improves progression-free survival in inoperable or metastatic stomach cancer, following a similar Phase III readout in November.

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Astellas now has two succesful Phase III readouts for zolbetuximab • Source: Shutterstock

Astellas Pharma, Inc. has posted its second positive Phase III trial readout for its first-in-class Claudin-18.2 antibody therapy in stomach cancer, moving a candidate the Japanese pharma has called vital to its strategy in gastric cancer treatment closer to filing for approval globally. Zolbetuximab (IMAB362) has met the primary endpoint of progression-free survival (PFS) as well as an overall survival secondary endpoint in the Phase III GLOW trial, Astellas reported on 16 December.

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