Inozyme Targets Underserved Mineralization Disorders Market With First-In-Class Enzyme Therapy

Emerging Company Profile: Fresh from a $73m follow-on offering last year, the US biotech is readying its lead asset for a pivotal trial in ultra-rare but debilitating mineralization disorders that affect infants and children.  

Emerging Company Profile: Inozyme Pharma
ENPP1 Deficiency Can Cause Arterial Calcification And Eventual Death • Source: Shutterstock

Inozyme Pharma Inc. is on a mission to treat two ultra-rare and often fatal mineralization disorders that currently have no approved options with its lead enzyme therapy asset that has the potential to be a ‘pipeline in a product.’

The Boston, MA-headquartered had a strong start with a $50m seed funding in January 2017 followed by a second private...

Scrip Podcast

Keep up with the top pharma business news of the week. On the go.

Scrip brings you a weekly bulletin of top picks.

More from Emerging Company Profiles

Scrip-Business (Free-1): Top-Selling Drugs 2024: Keytruda, Ozempic And Dupixent Dominate

 
• By 

Merck’s immuno-oncology blockbuster was the world’s best-selling drugs by revenues for the second year in a row, with an almost $12bn lead over its closest rival, Novo Nordisk’s GLP-1 drug Ozempic.

Empress Looks To The Body’s Internal Chemistry For Drug Leads

 
• By 

Emerging Company Profile: Backed by Flagship Pioneering, Empress deploys its Chemilogics platform to seek leads for small molecule therapies in inflammation, immunology, cancer and metabolic disease.

Mythic Therapeutics Faces An Acid Test

 

Emerging Company Profile: Efficacy data on the young group’s first pH-engineered antibody-drug conjugate could come next year, and potential partners will be watching.    

Emergex Goes To Battle Against ‘The Nasties’

 

Emerging Company Profile: The eight-year-old vaccine firm is planning clinical trials in the Philippines and Brazil to see how its synthetic viral peptide vaccine technology stands up against coronaviruses and dengue fever.

More from Start-Ups & SMEs

Pathalys Raises $105m To Pave Path Toward US Commercialization

 
• By 

The start-up launched last year with Phase III-ready upacicalcet, which has nearly completed two pivotal trials in secondary hyperparathyroidism and for which it has exclusive rights outside of Asia.

Empress Looks To The Body’s Internal Chemistry For Drug Leads

 
• By 

Emerging Company Profile: Backed by Flagship Pioneering, Empress deploys its Chemilogics platform to seek leads for small molecule therapies in inflammation, immunology, cancer and metabolic disease.

Syros’s AML Failure Sparks MDS Program Jitters, But Fears May Be Overblown

 

Discontinuation of the AML study created concern about potential readthrough to a pivotal MDS trial, but the company and analysts pointed out differences in the diseases.