Vir’s VIR-2482 Flunks In Phase II As Company Shifts Focus To Other Programs

 
• By Alaric DeArment
  
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Negative results from the PENINSULA study cast doubt on a Phase Ib study of the antibody in elderly adults. The company unveiled its next-generation flu drug, VIR-2981.

Vir said its trial of VIR-2482 in influenza A prevention was unsuccessful • Source: Shutterstock

Vir Biotechnology, Inc.’s respiratory antiviral franchise has met its second setback in less than a year with the failure of the Phase II PENINSULA study of VIR-2482 for the prevention of symptomatic influenza A, meaning the program does not likely have a path forward. However, the company pointed out that it has a significant cash runway, with about $1.9bn in cash and investments, giving it enough room to continue investing in current and future programs.

Vir said 20 July that PENINSULA, which enrolled nearly 3,000 men and women, failed to meet its primary or secondary...

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