J&J Looks To Erode Competitors’ Convenience Advantage With BCMA Bispecific

 
• By Alaric DeArment
  
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A Phase II study is exploring outpatient dosing of Tecvayli in multiple myeloma, while the company is moving the drug from weekly to biweekly and monthly dosing schedules.

J&J's booth at ASH 2023 • Source: Scrip

With Johnson & Johnson’s Tecvayli (teclistamab-cqyv) having the distinction of being the first BCMAxCD3-directed bispecific antibody for multiple myeloma to clear the US Food and Drug Administration, competitors with agents that have shown roughly comparable safety-efficacy profiles have lined up to win on convenience and the opportunity for more widespread use of their drugs. But J&J has been working to counteract their advantages by making Tecvayli administration less burdensome, as evidenced by some presentations at the recent American Society of Hematology annual meeting.

Tecvayli was the subject of multiple presentations at ASH, alongside J&J’s other approved and investigational products for multiple myeloma, including...

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