The biopharma industry’s fate lies largely in its R&D success and failures. Here, Scrip looks at five clinical trial failures that got readers clicking in 2023. Some were more comprehensive than others, highlighting the nuance that can be injected into clinical data in different settings and subgroups.
In November, one of Bayer AG’s main pipeline hopes, asundexian, crashed in the Phase III OCEANIC-AF trial, piling up the problems in new CEO Bill Anderson’s in-tray.
The oral Factor XIa inhibitor was bested by the control drug apixaban (BMS/Pfizer’s Factor Xa inhibitor Eliquis) in patients with...