Things Get Worse For Gilead’s Magrolimab

Company Pauses Solid Tumor Study Enrollment

 
• By Alaric DeArment
  
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Gilead said the FDA requested a partial clinical hold on the studies as well, just over a week after the drug maker said it would not develop the magrolimab further for blood cancers.

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Days after announcing it was calling off further development of the CD47 inhibitor magrolimab in hematological cancers, Gilead Sciences, Inc. is hitting the brakes on clinical trials of the drug in solid tumors as well, at least for now. It’s only the latest hit to a multibillion-dollar effort to develop what had been seen as an immuno-oncology agent with potentially broad applicability in oncology.

The Foster City, CA-based drug maker said 15 February that it has paused enrollment globally in studies of magrolimab in...

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