AbbVie Claims Rinvoq Superiority To Dupixent In AD

 
• By Joseph Haas
  
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In a head-to-head study of Rinvoq versus Dupixent in atopic dermatitis, the AbbVie drug showed superiority on a composite endpoint measuring skin clearance and itch resolution.

Head to head battle
Rinvoq shows efficacy edge vs. Dupixent in head-to-head trial • Source: Alamy

Fighting for market position in atopic dermatitis with Sanofi/Regeneron Pharmaceuticals, Inc.’s established Dupixent (dupilumab), AbbVie Inc. reported data from a Phase IIIb/IV head-to-head study on 25 April that it asserts demonstrates Rinvoq’s (upadacitinib) superiority on a stringent primary dual endpoint measuring complete skin clearance and little to no itch.

Key Takeaways

  • In the first head-to-head study of Rinvoq versus Dupixent in moderate-to-severe atopic dermatitis including adolescent patients, Rinvoq demonstrated superiority on a composite endpoint of nearly full skin clearance and zero or little itch.

AbbVie VP-global head of immunology clinical development Kori Wallace told Scrip that the study’s outcome “elevates the standard of care...

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