Viking Bolsters MASH Case With 52-Week Histology Data

 
• By Joseph Haas
  
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Viking will look to plan a Phase III program with the FDA after showing 52-week success on MASH resolution and fibrosis reduction with VK2809. The firm still hopes to move forward with a partner.

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Viking's 52-week biopsy data bolster case for VK2809 in MASH

Slightly more than one year after reporting 12-week data from its Phase IIb VOYAGE trial showing that VK-2809 can significantly reduce liver fat content in metabolic-associated steatohepatitis (MASH), Viking Therapeutics, Inc. bolstered those findings on 4 June with 52-week, histologic data from the study that also demonstrated a statistically significant benefit on reducing fibrosis.

Key Takeaways

  • Viking reports 52-week biopsy data for VK2809 in MASH, bolstering the case made with 12-week data in 2023 for MASH resolution with the drug.

The data position the San Diego-based firm to seek an end-of-Phase II meeting with the US Food and Drug Administration...

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